FAT4 Polyclonal Antibody | Invitrogen PA5-72970 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FAT4 Polyclonal Antibody

catalog :

PA5-72970

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 3

Reference
Kung C, Fang W, Hung Y, Huang K, Chen M, Chao Y, et al. Comparison of the mutation patterns between tumor tissue and cell-free DNA in stage IV gastric cancer. Aging (Albany NY). 2023;15:777-790 pubmed publisher
Wang S, Wang Z, Wu Y, Hou C, Dai X, Wang Q, et al. The TCM Prescription Yi-Fei-Jie-Du-Tang Inhibit Invasive Migration and EMT of Lung Cancer Cells by Activating Autophagy. Evid Based Complement Alternat Med. 2022;2022:9160616 pubmed publisher
Huang F, Wong D, Seto W, Mak L, Cheung T, Yuen M. Tumor suppressive role of mitochondrial sirtuin 4 in induction of G2/M cell cycle arrest and apoptosis in hepatitis B virus-related hepatocellular carcinoma. Cell Death Discov. 2021;7:88 pubmed publisher

product information

Product Type :

Antibody

Product Name :

FAT4 Polyclonal Antibody

Catalog # :

PA5-72970

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: Assay-Dependent

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by secretase to release intracellular domain (ICD). FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1. FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.

Immunogen :

A synthetic peptide made to a C-terminal portion of the human FAT4 protein (between residues 4000-4500) [UniProt Q6V0I7]

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: Assay-Dependent

Aliases :

6030410K14Rik; 9430004M15; Cadherin family member 14; cadherin-related family member 11; CDHF14; CDHR11; FAT atypical cadherin 4; FAT tumor suppressor homolog 4; FAT tumor suppressor homolog 4 (Drosophila); FAT4; Fatj; FAT-J; fat-like cadherin protein FAT-J; hFat4; HKLLS2; Nbla00548; protocadherin Fat 4; putative protein product of Nbla00548; RGD1564291; VMLDS2