NOX4 Polyclonal Antibody | Invitrogen PA5-72922 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NOX4 Polyclonal Antibody

catalog :

PA5-72922

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine, pigs , domestic sheep, domestic rabbit

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

product information

Product Type :

Antibody

Product Name :

NOX4 Polyclonal Antibody

Catalog # :

PA5-72922

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Human, Mouse, Non-human primate, Ovine, Porcine, Rabbit, Rat

Applications :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 2 ug/mL

Species :

Bovine, Human, Mouse, Non-human primate, Ovine, Porcine, Rabbit, Rat

Isotype :

IgG

Storage :

4 C, do not freeze

Description :

Oxygen sensing is essential for homeostasis in all aerobic organisms. A phagocyte-type oxidase, similar to that responsible for the production of large amounts of reactive oxygen species (ROS) in neutrophil granulocytes, with resultant antimicrobial activity, has been postulated to function in the kidney as an oxygen sensor that regulates the synthesis of erythropoietin in the renal cortex. NOX4 has a role as a redox messenger in the activation of intracellular signaling pathways leading (or contributing) to mitochondriogenesis, cell survival, and differentiation in hematopoietic stem cells. Data suggests that NOX4 provides a novel link between the insulin receptor and the generation of cellular reactive oxygen species that enhances insulin signal transduction.

Immunogen :

A synthetic peptide made to an internal region of the human NOX4 protein (between residues 100-200) [UniProt Q9NPH5].

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 2 ug/mL

Aliases :

AI648021; kidney oxidase-1; Kidney superoxide-producing NADPH oxidase; KOX; KOX1; KOX-1; NADPH oxidase 4; NOX 4; NOX4; NOX-4; renal NAD(P)H-oxidase; RENOX; superoxide-generating NADPH oxidase 4