This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PKN1 Polyclonal Antibody
catalog :
PA5-72912
quantity :
50 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
PKN1 Polyclonal Antibody
Catalog # :
PA5-72912
Quantity :
50 uL
Price :
US 464.00
Clonality :
Polyclonal
Host :
Rabbit
Reactivity :
Canine, Human, Mouse, Rat
Applications :
Immunohistochemistry (Paraffin): 1:1,000-1:5,000, Immunoprecipitation: 1:50-1:200, Western Blot: 1:1,000-1:2,000
Species :
Canine, Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
PKN1 (PRK1) belongs to the protein kinase C superfamily. This kinase is activated by the Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can also be activated by phospholipids. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Immunogen :
A synthetic peptide corresponding to amino acis 911-929 of human PKN1 was used as immunogen; GenBank no. gi 914098 gb AAB33345.1.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:1,000-1:5,000, Immunoprecipitation: 1:50-1:200, Western Blot: 1:1,000-1:2,000
Aliases :
DBK; F730027O18Rik; PAK1; PAK-1; PKN; PKN1; PKN-ALPHA; PRK1; Prkcl1; Protease-activated kinase 1; protein kinase C-like 1; Protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase N1; protein kinase PKN; protein kinase PKN-alpha; Protein-kinase C-related kinase 1; serine/threonine kinase 3; serine/threonine protein kinase N; serine/threonine-protein kinase N1; serine-threonine kinase N; serine-threonine protein kinase N; Stk3
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA