This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Jagged1 Polyclonal Antibody
catalog :
PA5-72843
quantity :
100 ug
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section
citations: 7
Reference
Ham S, Kim J, Seo S, Hong N, Park M, Kim Y, et al. Annexin A2 Stabilizes Oncogenic JAG1 Intracellular Domain by Inhibiting Proteasomal Degradation in Glioblastoma Cells. Int J Mol Sci. 2023;24: pubmed publisher
Chen J, Wang X, Zhang X, Yin J, Zheng Y. Jagged 1 Regulates The Proliferation and Metastasis of Human MDA-T68 Thyroid Cancer Cells. Cell J. 2023;25:399-406 pubmed publisher
Gong M, Yan F, Yu L, Li F. A dopamine-methacrylated hyaluronic acid hydrogel as an effective carrier for stem cells in skin regeneration therapy. Cell Death Dis. 2022;13:738 pubmed publisher
Lustofin S, Kami x144 ska A, Brzoskwinia M, Cyran J, Kotula Balak M, Bili x144 ska B, et al. Nuclear and Membrane Receptors for Sex Steroids Are Involved in the Regulation of Delta/Serrate/LAG-2 Proteins in Rodent Sertoli Cells. Int J Mol Sci. 2022;23: pubmed publisher
van Ingen E, van den Homberg D, van der Bent M, Mei H, Papac Milicevic N, Kremer V, et al. C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2'O-ribose methylation. Hum Mol Genet. 2022;31:1051-1066 pubmed publisher
Cheng F, Qin W, Yang A, Yan F, Chen Y, Ma J. Propofol alleviates neuropathic pain in chronic constriction injury rat models via the microRNA-140-3p/Jagged-1 peptide/Notch signaling pathway. Synapse. 2021;75:e22219 pubmed publisher
Kaminska A, Marek S, Pardyak L, Brzoskwinia M, Pawlicki P, Bilinska B, et al. Disruption of androgen signaling during puberty affects Notch pathway in rat seminiferous epithelium. Reprod Biol Endocrinol. 2020;18:30 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Jagged1 Polyclonal Antibody
Catalog # :
PA5-72843
Quantity :
100 ug
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1-2 ug/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Immunogen :
JAG1 antibody for a 19 amino acid peptide near the carboxy terminus of human JAG1. The immunogen is within the last 50 amino acids of JAG1.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1-2 ug/mL
Aliases :
ABE2; AGS; AHD; AWS; CD339; Gsfabe2; HJ1; Htu; JAG1; jagged 1; jagged canonical Notch ligand 1; Jagged1; JAGL1; Ozz; protein jagged-1; Ser-1; Serrate-1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA