UVRAG Polyclonal Antibody | Invitrogen PA5-72818 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

UVRAG Polyclonal Antibody

catalog :

PA5-72818

quantity :

100 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

UVRAG Polyclonal Antibody

Catalog # :

PA5-72818

Quantity :

100 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ELISA: Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1-2 ug/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

UVRAG is predicted to contain a coiled-coil structure and is likely to be metabolically unstable based on the occurrence of a strong PEST domain. It interacts with Beclin 1, leading to activation of autophagy and thereof inhibition of tumorigenicity of human colon cancer cells. The gene for UVRAG protein is localized on human chromosome 11q13. 5 and complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells. The gene has been extremely well conserved during evolution, implying an important role for this gene product in cell metabolism. Chromosomal aberrations involving this gene are associated with left-right axis malformation, and mutations in this gene have been associated with colon cancer. The protein is highly expressed in human brain, lung, kidney and liver.

Immunogen :

UVRAG antibody for an 18 amino acid peptide near the carboxy terminus of human UVRAG. The immunogen is within amino acids 490 - 540 of UVRAG.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1-2 ug/mL

Aliases :

9530039D02Rik; AI648770; BB124205; beclin 1 binding protein; DHTX; disrupted in heterotaxy; hypothetical protein; p63; UV radiation resistance associated; UV radiation resistance associated gene; UV radiation resistance-associated gene protein; UV radiation resistance-associated protein; UVRAG; Uvrag1; Uvragl; VPS38