This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SIGLEC15 Polyclonal Antibody
catalog :
PA5-72765
quantity :
100 ug
price :
US 460.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section
citations: 7
Reference
Chen Q, Chen B, Wang C, Hu L, Wu Q, Zhu Y, et al. Dynamic change in Siglec-15 expression in peritumoral macrophages confers an immunosuppressive microenvironment and poor outcome in glioma. Front Immunol. 2023;14:1159085 pubmed publisher
Sheng K, Wu Y, Lin H, Fang M, Xue C, Lin X, et al. Transcriptional Regulation of Siglec-15 by ETS-1 and ETS-2 in Hepatocellular Carcinoma Cells. Int J Mol Sci. 2023;24: pubmed publisher
Lu Z, Cheng P, Huang F, Li J, Wang B, Zou S, et al. Significance of Siglec-15 expression in colorectal cancer: association with advanced disease stage and fewer tumor-infiltrating lymphocytes. J Pathol Clin Res. 2023;9:121-128 pubmed publisher
Zhao Y, Lv J, Zhang H, Xie J, Dai H, Zhang X. Gene Expression Profiles Analyzed Using Integrating RNA Sequencing, and Microarray Reveals Increased Inflammatory Response, Proliferation, and Osteoclastogenesis in Pigmented Villonodular Synovitis. Front Immunol. 2021;12:665442 pubmed publisher
Fudaba H, Momii Y, Hirakawa T, Onishi K, Asou D, Matsushita W, et al. Sialic acid-binding immunoglobulin-like lectin-15 expression on peritumoral macrophages is a favorable prognostic factor for primary central nervous system lymphoma patients. Sci Rep. 2021;11:1206 pubmed publisher
Li B, Zhang B, Wang X, Zeng Z, Huang Z, Zhang L, et al. Expression signature, prognosis value, and immune characteristics of Siglec-15 identified by pan-cancer analysis. Oncoimmunology. 2020;9:1807291 pubmed publisher
Hao J, Nong J, Zhao D, Li H, Su D, Zhou L, et al. The significance of Siglec-15 expression in resectable non-small cell lung cancer. Neoplasma. 2020;67:1214-1222 pubmed publisher
product information
Product Type :
Antibody
Product Name :
SIGLEC15 Polyclonal Antibody
Catalog # :
PA5-72765
Quantity :
100 ug
Price :
US 460.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: Assay-Dependent, Immunohistochemistry (Paraffin): 2.5 ug/mL, Western Blot: 1.0-2.0 ug/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Binds sialylated glycoproteins.
Immunogen :
SIGLEC15 antibody for a 15 amino acid synthetic peptide near the amino terminus of human SIGLEC15. The immunogen is within amino acids 50 - 100 of SIGLEC15.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-Dependent, Immunohistochemistry (Paraffin): 2.5 ug/mL, Western Blot: 1.0-2.0 ug/mL
Aliases :
CD33 antigen-like 3; CD33 molecule-like 3; Cd33l3; EG620235; HsT1361; RGD1565948; sialic acid binding Ig like lectin 15; sialic acid binding Ig-like lectin 15; sialic acid-binding Ig-like lectin 15; Siglec; Siglec 15; SIGLEC15; Siglec-15; SIGLEC-I
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA