COMP Polyclonal Antibody | Invitrogen PA5-72491 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

COMP Polyclonal Antibody

catalog :

PA5-72491

quantity :

400 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Laudon J, Whittaker J, Ren G, Jaremko J, Emery C, Krawetz R. Serum cartilage oligomeric matrix protein (COMP) expression in individuals who sustained a youth sport-related intra-articular knee injury 3-10 years previously and uninjured matched controls. Osteoarthritis Cartilage. 2019;27:286-293 pubmed publisher

product information

Product Type :

Antibody

Product Name :

COMP Polyclonal Antibody

Catalog # :

PA5-72491

Quantity :

400 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography, Protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Flow Cytometry: 1:25, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:2,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

Immunogen :

KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human COMP

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:25, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:2,000

Aliases :

Cartilage oligomeric matrix protein; cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple); cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple); Comp; EDM1; EPD1; MED; MGC131819; MGC149768; PSACH; pseudoachondroplasia (epiphyseal dysplasia 1, multiple); putative cartilage oligomeric matrix protein; THBS5; Thrombospondin5; Thrombospondin-5; TSP 5; TSP5