This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NOX4 Polyclonal Antibody
catalog :
PA5-72444
quantity :
100µL
price :
US 345
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
NOX4 Polyclonal Antibody
Catalog # :
PA5-72444
Quantity :
100µL
Price :
US 345
Clonality :
Polyclonal
Purity :
selective precipitation
Host :
Rabbit
Reactivity :
Canine, Human, Mouse, Rat
Applications :
Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: Assay-Dependent
Species :
Canine, Human, Mouse, Rat
Isotype :
IgG
Storage :
-20°C
Description :
Oxygen sensing is essential for homeostasis in all aerobic organisms. A phagocyte-type oxidase, similar to that responsible for the production of large amounts of reactive oxygen species (ROS) in neutrophil granulocytes, with resultant antimicrobial activity, has been postulated to function in the kidney as an oxygen sensor that regulates the synthesis of erythropoietin in the renal cortex. NOX4 has a role as a redox messenger in the activation of intracellular signaling pathways leading (or contributing) to mitochondriogenesis, cell survival, and differentiation in hematopoietic stem cells. Data suggests that NOX4 provides a novel link between the insulin receptor and the generation of cellular reactive oxygen species that enhances insulin signal transduction.
Format :
Liquid
Applications w/Dilutions :
Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: Assay-Dependent
Aliases :
AI648021; BOS_24390; Kidney oxidase-1; Kidney superoxide-producing NADPH oxidase; Kox; KOX1; KOX-1; NADPH oxidase 4; NOX 4; NOX4; NOX-4; Renal NAD(P)H-oxidase; Renox; Superoxide-generating NADPH oxidase 4
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA