SFTPC Polyclonal Antibody | Invitrogen PA5-71680 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SFTPC Polyclonal Antibody

catalog :

PA5-71680

quantity :

200 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 7

Reference
Li D, Xu X, Hu Y, Cui Q, Xiao Y, Sun S, et al. Congenital heart disease-associated pulmonary dysplasia and its underlying mechanisms. Am J Physiol Lung Cell Mol Physiol. 2023;324:L89-L101 pubmed publisher
He H, Yang W, Su N, Zhang C, Dai J, Han F, et al. Activating NO-sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury. J Exp Med. 2023;220: pubmed publisher
Zhang M, Ali G, Komatsu S, Zhao R, Ji H. Prkg2 regulates alveolar type 2-mediated re-alveolarization. Stem Cell Res Ther. 2022;13:111 pubmed publisher
Bradford L, Ross M, Minso J, Cernelc Kohan M, Shayan K, Wong S, et al. Interstitial lung disease in children with Rubinstein-Taybi syndrome. Pediatr Pulmonol. 2022;57:264-272 pubmed publisher
Brookes O, Boland S, Lai Kuen R, Miremont D, Movassat J, Baeza Squiban A. Co-culture of type I and type II pneumocytes as a model of alveolar epithelium. PLoS ONE. 2021;16:e0248798 pubmed publisher
Jia X, Wu B, Huang J, Fan L, Yang M, Xu W. YAP and Wnt3a independently promote AECIIs proliferation and differentiation by increasing nuclear β‑catenin expression in experimental bronchopulmonary dysplasia. Int J Mol Med. 2021;47:195-206 pubmed publisher
Krishnamurthy S, Wohlford Lenane C, Kandimalla S, Sartre G, Meyerholz D, Théberge V, et al. Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia. Nat Commun. 2019;10:4906 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SFTPC Polyclonal Antibody

Catalog # :

PA5-71680

Quantity :

200 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography, Protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 1:25, Immunocytochemistry: 1:25, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:2,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Immunogen :

KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SFTPC

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:25, Immunocytochemistry: 1:25, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:2,000

Aliases :

BRICD6; BRICHOS domain containing 6; LOW QUALITY PROTEIN: pulmonary surfactant-associated protein C; pro-SpC; PSP C; PSP-C; pulmonary surfactant apoprotein-2 SP-C; pulmonary surfactant associated protein C; pulmonary surfactant protein C; pulmonary surfactant-associated protein C; Pulmonary surfactant-associated proteolipid SPL(Val); SFTP 2; SFTP2; Sftp-2; Sftpc; SMDP2; SP C; SP5; SPC; SP-C; surfactant associated protein C; surfactant protein C; Surfactant pulmonary-associated protein C; Surfactant, pulmonary-associated protein C; surfactant-associated protein; type I SP-C; type I surfactant protein C; type II SP-C; type II surfactant protein C