YTHDF2 Polyclonal Antibody | Invitrogen PA5-70853 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

YTHDF2 Polyclonal Antibody

catalog :

PA5-70853

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 1

Reference
Semenovykh D, Benak D, Holzerová K, Cerna B, Telensky P, Vavrikova T, et al. Myocardial m6A regulators in postnatal development: effect of sex. Physiol Res. 2022;71:877-882 pubmed

product information

Product Type :

Antibody

Product Name :

YTHDF2 Polyclonal Antibody

Catalog # :

PA5-70853

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 1.0 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation. Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5'-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation.

Immunogen :

synthetic peptide directed towards the C-terminal region of human YTHDF2

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1.0 ug/mL

Aliases :

9430020E02Rik; CAHL; CLL-associated antigen KW-14; HGRG8; high glucose-regulated protein 8; high-glucose-regulated protein 8; LOW QUALITY PROTEIN: YTH domain-containing family protein 2; NY-REN-2; renal carcinoma antigen NY-REN-2; YTH domain family 2; YTH domain family protein 2; YTH domain family, member 2; YTH domain-containing family protein 2; YTH N(6)-methyladenosine RNA binding protein 2; YTH N6-methyladenosine RNA binding protein 2; yth2; YTHDF2; zgc:56224