CH25H Polyclonal Antibody | Invitrogen PA5-70691 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CH25H Polyclonal Antibody

catalog :

PA5-70691

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 1

Reference
Chen C, Ji H, Jiang N, Wang Y, Zhou Y, Zhu Z, et al. Thrombin increases the expression of cholesterol 25-hydroxylase in rat astrocytes after spinal cord injury. Neural Regen Res. 2023;18:1339-1346 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CH25H Polyclonal Antibody

Catalog # :

PA5-70691

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Surface plasmon resonance: Assay-dependent, Western Blot: 1.0 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes (PubMed:9852097). Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.

Immunogen :

synthetic peptide directed towards the C-terminal region of human CH25H

Format :

Liquid

Applications w/Dilutions :

Surface plasmon resonance: Assay-dependent, Western Blot: 1.0 ug/mL

Aliases :

1.14.99.38; AI462618; C25H; CH25H; ch25hb; cholesterol 25-hydroxylase; Cholesterol 25-hydroxylase-like protein; cholesterol 25-monooxygenase; h25OH; m25OH; Unknown (protein for MGC:143045); zgc:101688