AVPR1B Polyclonal Antibody | Invitrogen PA5-70604 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

AVPR1B Polyclonal Antibody

catalog :

PA5-70604

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Product Type :

Antibody

Product Name :

AVPR1B Polyclonal Antibody

Catalog # :

PA5-70604

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 1.0 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Vasopressin V1B receptor expression has been documented in the pituitary, pituitary tumors, pheochromocytoma, breast cancer, and small-cell lung carcinomas. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Immunogen :

synthetic peptide directed towards the middle region of human V1b Receptor (aa 271-320)

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1.0 ug/mL

Aliases :

Antidiuretic hormone receptor 1b; arginine vasopressin receptor 1B; arginine vasopressin receptor 3; arginine vasopressin receptor V3; arginine vasopressin type 1b receptor; AVP receptor V3; AVPR V1b; AVPR V3; Avpr1b; AVPR3; pituitary vasopressin receptor 3; V1b receptor; V1bR; V3/V1b; V3/V1b pituitary vasopressin receptor; vasopressin V1b receptor; Vasopressin V3 receptor; VIBR; VPR3