KLF15 Polyclonal Antibody | Invitrogen PA5-70374 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KLF15 Polyclonal Antibody

catalog :

PA5-70374

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot

product information

Product Type :

Antibody

Product Name :

KLF15 Polyclonal Antibody

Catalog # :

PA5-70374

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Mouse

Applications :

Western Blot: 1.0 ug/mL

Species :

Mouse

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

KLF15 is a nuclear protein belonging to the Sp1 C2H2-type zinc-finger protein family with three C2H2-type zinc fingers. A transcriptional activator, KLF15 binds to the GA element of the CLCNKA promoter and may help to regulate the strict tissue and nephron segment-specific expression of CLCNKA and CLCNKB channel genes. It plays an essential role in adipogenesis in cells through its regulation of PPARG expression. Reports suggest that KLF15 is an inhibitor of cardiac hypertrophy and functions in a pathway, regulating the cardiac response to hemodynamic stress, and regulates mitochondrial acetyl-CoA synthase expression in skeletal muscle. KLF15 may also act as a transcriptional repressor of the rhodopsin and IRBP promoters in the retina, and is a possible participant in repression of photoreceptor-specific gene expression in nonphotoreceptor cells. It is highly expressed in liver, followed by heart, skeletal muscle, and kidney but not expressed in bone marrow or lymphoid tissues.

Immunogen :

synthetic peptide directed towards the N-terminal region of KLF15

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1.0 ug/mL

Aliases :

1810013I09Rik; AV048136; AW494632; Cardiovascular Krueppel-like factor; CKLF; DKFZp779M1320; Kidney-enriched krueppel-like factor; kidney-enriched Kruppel-like factor; KKLF; KKLF protein; Klf15; KLF15; transcription factor; Krueppel-like factor 15; Kruppel like factor 15; Kruppel-like factor 15