This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PCID2 Polyclonal Antibody
catalog :
PA5-70296
quantity :
100 uL
price :
US 454.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
rat
application :
western blot
product information
Product Type :
Antibody
Product Name :
PCID2 Polyclonal Antibody
Catalog # :
PA5-70296
Quantity :
100 uL
Price :
US 454.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Rat
Applications :
Western Blot: 1.0 ug/mL
Species :
Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells.
Immunogen :
synthetic peptide corresponding to a region of rat PCID2
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1.0 ug/mL
Aliases :
A730042J05Rik; CSN12-like protein; F10; fa11f03; HT004; hypothetical protein LOC617943; ik:tdsubc_1e10; im:6909928; PCI domain containing 2; PCI domain-containing protein 2; Pcid2; RGD1307041; RP11-98F14.6; tdsubc_1e10; wu:fa11f03; xx:tdsubc_1e10; zgc:101845
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA