CRYGS Polyclonal Antibody | Invitrogen PA5-69837 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CRYGS Polyclonal Antibody

catalog :

PA5-69837

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

rat

application :

western blot

product information

Product Type :

Antibody

Product Name :

CRYGS Polyclonal Antibody

Catalog # :

PA5-69837

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Rat

Applications :

Western Blot: 1.0 ug/mL

Species :

Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. This gene encodes a protein initially considered to be a beta-crystallin but the encoded protein is monomeric and has greater sequence similarity to other gamma-crystallins. This gene encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Immunogen :

synthetic peptide directed towards the middle region of human CRYGS (aa 129-178)

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1.0 ug/mL

Aliases :

AI327013; Beta-crystallin S; beta-crystallin S-like protein; CRYG8; CRYGS; crystallin gamma S; crystallin, gamma 8; crystallin, gamma polypeptide 8; crystallin, gamma S; CTRCT20; Gamma-crystallin S; gamma-crystallin S; beta-crystallin S; gamma-S-crystallin; gammaS-crystallin; opacity due to poor secondary fiber cell junction; Opj; recessive nuclear cataract; rncat; unnamed protein product