SENP6 Polyclonal Antibody | Invitrogen PA5-69704 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SENP6 Polyclonal Antibody

catalog :

PA5-69704

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot

citations: 1

Reference
Theurillat I, Hendriks I, Cossec J, Andrieux A, Nielsen M, Dejean A. Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells. Cell Rep. 2020;32:108146 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SENP6 Polyclonal Antibody

Catalog # :

PA5-69704

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Mouse

Applications :

Western Blot: 1.0 ug/mL

Species :

Mouse

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Ubiquitin-like molecules, such as SUMO1, are structurally related to ubiquitin. and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1. to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins. SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates.

Immunogen :

synthetic peptide directed towards the middle region of human SENP6 (aa 788-837)

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1.0 ug/mL

Aliases :

2810017C20Rik; E130319N12Rik; FKSG6; FLJ11355; FLJ11887; KIAA0389; KIAA0797; mKIAA0797; RP1-134M13.1; SENP6; sentrin/SUMO-specific protease SENP6; Sentrin-specific protease 6; Sentrin-specific protease 6-like protein; SSP1; SUMO specific peptidase 6; SUMO/sentrin specific peptidase 6; SUMO/sentrin specific protease 6; SUMO1/sentrin specific peptidase 6; SUMO1/sentrin specific protease 6; Sumo1/sentrin/SMT3 specific peptidase 6; SUMO-1-specific protease 1; Susp1