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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CPT1A Polyclonal Antibody
catalog :
PA5-69347
quantity :
100 uL
price :
US 454.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 3a
Trabjerg M, Andersen D, Huntjens P, Oklinski K, Bolther L, Hald J, et al. Downregulating carnitine palmitoyl transferase 1 affects disease progression in the SOD1 G93A mouse model of ALS. Commun Biol. 2021;4:509 pubmed publisher
Abd El Haleim E, Sallam N. Vitamin D modulates hepatic microRNAs and mitigates tamoxifen-induced steatohepatitis in female rats. Fundam Clin Pharmacol. 2022;36:338-349 pubmed publisher
Zeng F, Yao M, Wang Y, Zheng W, Liu S, Hou Z, et al. Fatty acid β-oxidation promotes breast cancer stemness and metastasis via the miRNA-328-3p-CPT1A pathway. Cancer Gene Ther. 2021;: pubmed publisher
product information
Product Type :
Antibody
Product Name :
CPT1A Polyclonal Antibody
Catalog # :
PA5-69347
Quantity :
100 uL
Price :
US 454.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Immunohistochemistry: 1:200, Western Blot: 0.2-1.0 ug/mL
Species :
Human
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen :
synthetic peptide directed towards the middle region of human CPT1A
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry: 1:200, Western Blot: 0.2-1.0 ug/mL
Aliases :
C730027G07; carnitine O-palmitoyltransferase; carnitine O-palmitoyltransferase 1, liver isoform; Carnitine O-palmitoyltransferase I, liver isoform; carnitine palmitoyl transferase I isoform; Carnitine palmitoyltransferase 1 alpha, liver isoform; carnitine palmitoyltransferase 1, liver; carnitine palmitoyltransferase 1A; carnitine palmitoyltransferase 1A (liver); carnitine palmitoyltransferase 1a, liver; carnitine palmitoyltransferase I, liver; CPT 1; CPT I; Cpt1; Cpt-1; CPT1 L; CPT1A; CPT1-L; CPTI; CPT-Ia; CPTI-L; L-CPT I; L-CPT1; mitochondrial carnitine palmitoyltransferase 1A
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA