Cytokeratin 14/17 Polyclonal Antibody | Invitrogen PA5-68451 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytokeratin 14/17 Polyclonal Antibody

catalog :

PA5-68451

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

Cytokeratin 14/17 Polyclonal Antibody

Catalog # :

PA5-68451

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:100-1:300, Western Blot: 1:10,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

Cytokeratins(CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. Skin) and non-keratinizing cells (ie. Mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. Atleast 20 different CKs in the molecular range of 40-70 k Da and isoelectric points of 5-805 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification. Belonging to the type A (acidic) subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas.

Immunogen :

Synthesized peptide derived from human Cytokeratin 14/17 [aa 261-310].

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:100-1:300, Western Blot: 1:10,000

Aliases :

39.1; AI626930; CK14; CK-14; CK-17; cytokeratin 14; cytokeratin-14; Cytokeratin-17; EBS3; EBS4; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; K17; Ka14; Ka17; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin 17; keratin 17, type I; keratin complex 1, acidic, gene 14; keratin complex 1, acidic, gene 17; keratin, type I cytoskeletal 14; Keratin, type I cytoskeletal 17; keratin-14; Keratin-17; Krt-1.14; Krt1-14; Krt1-17; KRT14; KRT17; krt17 {ECO:0000250; LOC100737113; NFJ; PC; PC2; PCHC1; type I keratin Ka14; Type I keratin Ka17; UniProtKB:Q04695}