KCNE1L Polyclonal Antibody | Invitrogen PA5-68274 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KCNE1L Polyclonal Antibody

catalog :

PA5-68274

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

Product Type :

Antibody

Product Name :

KCNE1L Polyclonal Antibody

Catalog # :

PA5-68274

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot: 1:1,000-1:3,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

Kcne1 is a member of Voltage-gated potassium (Kv) channels that represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. The diverse functions of Kv channels include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The Kcne1 gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily. Kcne1, an intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome. Functionally, Kcne1 is a potassium channel ancillary subunit that is essential for generation of some native K(+) currents by virtue of formation of heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. Kcne1 also functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1. Diseases associated with KCNE1 include Jervell And Lange-Nielsen Syndrome 2 and Long Qt Syndrome 5.

Immunogen :

Synthesized peptide derived from human KCNE1L.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000-1:3,000

Aliases :

1500015C14Rik; AMME syndrome candidate gene 2 protein; AMMECR2; AMMECR2 protein; cardiac voltage-gated potassium channel accessory subunit 5; KCNE1L; KCNE1-like; Kcne5; Mink; MinK-like protein; potassium channel subunit beta MiRP4; potassium channel, voltage gated subfamily E regulatory beta subunit 5; potassium channel, voltage-gated Isk-related subfamily E regulatory beta subunit 5; potassium voltage-gated channel subfamily E member 1-like protein; Potassium voltage-gated channel subfamily E regulatory beta subunit 5; potassium voltage-gated channel subfamily E regulatory subunit 5; potassium voltage-gated channel, Isk-related family, member 1-like; potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene; voltage-gated potassium channel accessory subunit 5