This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
WIT1 Polyclonal Antibody
catalog :
PA5-67998
quantity :
100 µL
price :
US 426
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
Product Type :
Antibody
Product Name :
WIT1 Polyclonal Antibody
Catalog # :
PA5-67998
Quantity :
100 µL
Price :
US 426
Clonality :
Polyclonal
Purity :
affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Western Blot: 1:1,000
Species :
Human
Isotype :
IgG
Storage :
-20°C
Description :
Wilms' tumor is a neoplasm of the kidneys that usually occurs in children and is characterized by the presence of abortive tubules and glomeruli surrounded by a spindled cell stroma. The 11p13 Wilms' tumor locus consists of two coordinately regulated transcripts, WT1 and WIT-1, which are mutated in Wilms' tumors. Wilms' tumor upstream neighbor 1 (WIT-1) is encoded by an intron-less gene upstream of the Wilms' tumor 1 (WT1) gene, which is is important for nephrogenesis and gonadal growth. The WT1 gene is bi-directionally transcribed from the same promoter region as WIT-1, which may function as an antisense regulator of WT1. WIT-1 and WT1 have the same temporal and cell-restricted expression pattern, although the expression of WIT-1 is less abundant. Methylation of the WIT-1 gene is implicated in hematologic malignancy of chemoresistant acute myeloid leukemia. Single nucleotide polymorphisms (SNPs) in the WIT-1 gene are significantly associated with focal segmental glomerulosclerosis.
Immunogen :
Synthesized peptide derived from human WIT1.
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:1,000
Aliases :
6030498F17; AI314831; Wilms tumor 1 homolog, opposite strand; WIT1; WIT-1; WT1 antisense RNA; WT1AS; Wt1-as; WT1-AS1; Wt1os
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA