UNC5B Polyclonal Antibody | Invitrogen PA5-67631 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

UNC5B Polyclonal Antibody

catalog :

PA5-67631

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Sawada J, Hiraoka N, Qi R, Jiang L, Fournier Goss A, Yoshida M, et al. Molecular Signature of Tumor-Associated High Endothelial Venules That Can Predict Breast Cancer Survival. Cancer Immunol Res. 2022;10:468-481 pubmed publisher
Wu S, Guo X, Zhou J, Zhu X, Chen H, Zhang K, et al. High expression of UNC5B enhances tumor proliferation, increases metastasis, and worsens prognosis in breast cancer. Aging (Albany NY). 2020;12:17079-17098 pubmed publisher

product information

Product Type :

Antibody

Product Name :

UNC5B Polyclonal Antibody

Catalog # :

PA5-67631

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunohistochemistry (Paraffin): 1:20-1:100

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity.

Immunogen :

Synthesized peptide derived from human UNC5B.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:20-1:100

Aliases :

6330415E02Rik; A630020F16; C. elegans; D10Bwg0792e; Netrin receptor UNC5B; p53RDL1; p53-regulated receptor for death and life protein 1; Protein unc-5 homolog 2; protein unc-5 homolog B; transmembrane receptor Unc5H2; unc5 homolog 2; unc-5 homolog 2; unc-5 homolog B; unc-5 homolog B (C. elegans); unc-5 netrin receptor B; Unc5b; UNC5H2; UNQ1883/PRO4326