Phospho-Nrf2 (Ser40) Polyclonal Antibody | Invitrogen PA5-67520 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-Nrf2 (Ser40) Polyclonal Antibody

catalog :

PA5-67520

quantity :

100 uL

price :

US 460.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 17

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 3d	Naguib S, Backstrom J, Gil M, Calkins D, Rex T. Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension. Redox Biol. 2021;42:101883 pubmed publisher
	Schiffer T, Carvalho L, Guimaraes D, Boeder A, Wikstr xf6 m P, Carlstr xf6 m M. Specific NOX4 Inhibition Preserves Mitochondrial Function and Dampens Kidney Dysfunction Following Ischemia-Reperfusion-Induced Kidney Injury. Antioxidants (Basel). 2024;13: pubmed publisher
	Sciandra F, Bottoni P, De Leo M, Braca A, Brancaccio A, Bozzi M. Verbascoside Elicits Its Beneficial Effects by Enhancing Mitochondrial Spare Respiratory Capacity and the Nrf2/HO-1 Mediated Antioxidant System in a Murine Skeletal Muscle Cell Line. Int J Mol Sci. 2023;24: pubmed publisher
	Naguib S, Backstrom J, Artis E, Ghose P, Stahl A, Hardin R, et al. NRF2/ARE mediated antioxidant response to glaucoma: role of glia and retinal ganglion cells. Acta Neuropathol Commun. 2023;11:171 pubmed publisher
	Lee H, Lee G, Kim J, Cheng J, Cho J, Suh J, et al. Ixeris dentata and Lactobacillus gasseri media protect against periodontitis through Nrf2-HO-1 signalling pathway. Sci Rep. 2023;13:12861 pubmed publisher
	Wu C, Feng C, Wang C, Wen Z, Long C, Tang F. Zinc Finger Protein 90 Knockdown Promotes Cisplatin Sensitivity via Nrf2/HO-1 Pathway in Ovarian Cancer Cell. Cancers (Basel). 2023;15: pubmed publisher
	Park C, Cha H, Kim D, Kwon C, Park S, Hong S, et al. Fisetin Protects C2C12 Mouse Myoblasts from Oxidative Stress-Induced Cytotoxicity through Regulation of the Nrf2/HO-1 Signaling. J Microbiol Biotechnol. 2023;33:591-599 pubmed publisher
	Schulz M, Dubourg V, Nolze A, Kopf M, Schwerdt G, Gekle M. Acidosis Activates the Nrf2 Pathway in Renal Proximal Tubule-Derived Cells through a Crosstalk with Renal Fibroblasts. Antioxidants (Basel). 2023;12: pubmed publisher
	Liu C, Chen M, Kuo Y, Cheng J, Chang L, Chang M, et al. Osthole Antagonizes Microglial Activation in an NRF2-Dependent Manner. Molecules. 2023;28: pubmed publisher
	Coleman D, Totakul P, Onjai Uea N, Aboragah A, Jiang Q, Vailati Riboni M, et al. Rumen-protected methionine during heat stress alters mTOR, insulin signaling, and 1-carbon metabolism protein abundance in liver, and whole-blood transsulfuration pathway genes in Holstein cows. J Dairy Sci. 2022;105:7787-7804 pubmed publisher
	Stratmann B, Eggers B, Mattern Y, Silva de Carvalho T, Marcus K, Tschoepe D. Chronic Hyperglycaemia Inhibits Tricarboxylic Acid Cycle in Rat Cardiomyoblasts Overexpressing Glucose Transporter Type 4. Int J Mol Sci. 2022;23: pubmed publisher
	Delaidelli A, Richner M, Jiang L, van der Laan A, Bergholdt Jul Christiansen I, Ferreira N, et al. α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response. Acta Neuropathol Commun. 2021;9:105 pubmed publisher
	Xue P, Hu X, Chang E, Wang L, Chen M, Wu T, et al. Deficiency of optineurin enhances osteoclast differentiation by attenuating the NRF2-mediated antioxidant response. Exp Mol Med. 2021;53:667-680 pubmed publisher
	Kim J, Choi Y, Lee S, Gong J, Lee Y, Sung J, et al. Antioxidant activity and laxative effects of tannin-enriched extract of Ecklonia cava in loperamide-induced constipation of SD rats. PLoS ONE. 2021;16:e0246363 pubmed publisher
	Đurašević S, Stojković M, Sopta J, Pavlović S, Borković Mitić S, Ivanović A, et al. The effects of meldonium on the acute ischemia/reperfusion liver injury in rats. Sci Rep. 2021;11:1305 pubmed publisher
	Han L, Batistel F, Ma Y, Alharthi A, Parys C, Loor J. Methionine supply alters mammary gland antioxidant gene networks via phosphorylation of nuclear factor erythroid 2-like 2 (NFE2L2) protein in dairy cows during the periparturient period. J Dairy Sci. 2018;101:8505-8512 pubmed publisher
	Han L, Zhou Z, Ma Y, Batistel F, Osorio J, Loor J. Phosphorylation of nuclear factor erythroid 2-like 2 (NFE2L2) in mammary tissue of Holstein cows during the periparturient period is associated with mRNA abundance of antioxidant gene networks. J Dairy Sci. 2018;101:6511-6522 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-Nrf2 (Ser40) Polyclonal Antibody

Catalog # :

PA5-67520

Quantity :

100 uL

Price :

US 460.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100, Western Blot: 1:1,000-1:3,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

Nfr1 (also designated TCF11), Nrf2 and Nfr3 are bZIP transcription factors that heterodimer with Maf proteins to bind MARE (Maf recognition elements) sequences. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein Keap1.

Immunogen :

Synthesized peptide derived from human Nrf2 around the phosphorylation site of S40.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Western Blot: 1:1,000-1:3,000

Aliases :

AI194320; E4TF1-60; E4TF1A; HEBP1; Nfe2l2; NF-E2-related factor 2; NFE2-related factor 2; NF-E2-related factor-2; NFT2; NRF2; NRF2A; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-like 2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2 like 2; nuclear factor, erythroid 2-like 2; nuclear factor, erythroid derived 2, like 2; Unknown (protein for IMAGE:7945830)

more info or order :

Invitrogen product webpage