RELM beta Polyclonal Antibody | Invitrogen PA5-61896 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RELM beta Polyclonal Antibody

catalog :

PA5-61896

quantity :

100 uL

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Steuer A, Scoggin K, Stewart J, Barker V, Adams A, Loynachan A, et al. Comparison of the host response to larvicidal and nonlarvicidal treatment of naturally acquired cyathostomin infections in horses. Parasite Immunol. 2022;44:e12941 pubmed publisher
Wang Y, Kim R, Sims C, Allbritton N. Building a Thick Mucus Hydrogel Layer to Improve the Physiological Relevance of In Vitro Primary Colonic Epithelial Models. Cell Mol Gastroenterol Hepatol. 2019;8:653-655.e5 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RELM beta Polyclonal Antibody

Catalog # :

PA5-61896

Quantity :

100 uL

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:200-1:500

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Adipose tissue is an energy reserve that is strictly regulated in animals. Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), perilipin, and resistin. Resistin, also known as Adipocyte Secreted Factor (ADSF) and FIZZ3, is a cytokine that is specifically secreted by adipocytes. While the function of resistin is not well understood, it appears to have key paracrine roles and has a suggested role in type 2 diabetes. Studies show that in obese, diabetic mice the levels of serum resistin are increased, which has an antagonistic effect on insulin. Additional studies have shown that resistin causes insulin resistance and glucose intolerance in mice. Resistin gene expression requires C/EBP alpha, which is necessary and sufficient for expression. Studies show that the coactivators CBP and p300, which have been shown to display histone acetyltransferase (HAT) activity, abundantly acetylate the histones at the resistin promoter suggesting their role in activating chromatin for resistin transcription. Numerous PPAR gamma and RXR ligands have been shown to downregulate resistin expression in adipocytes.

Immunogen :

Recombinant protein corresponding to Human RELM beta. Recombinant protein control fragment (Product # RP-98522 ).

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:200-1:500

Aliases :

9030012B21Rik; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 2; CCRG; Colon and small intestine-specific cysteine-rich protein; colon carcinoma-related gene protein; cysteine-rich secreted A12-alpha-like protein 1; cysteine-rich secreted protein A12-alpha-like 1; Cysteine-rich secreted protein A12-beta; cysteine-rich secreted protein FIZZ2; FIZZ1; Fizz2; found in inflammatory zone 1; found in inflammatory zone 2; HXCP2; Relmb; RELMbeta; RELM-beta; resistin like beta; resistin-like beta; resistin-like molecule beta; RETNL2; RETNLB; RSNB; UNQ408/PRO770; XCP2; Xcp3