This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
HBB Polyclonal Antibody
catalog :
PA5-60287
quantity :
100 uL
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 2
Reference
Zhang F, Zhang B, Wang Y, Jiang R, Liu J, Wei Y, et al. An extra-erythrocyte role of haemoglobin body in chondrocyte hypoxia adaption. Nature. 2023;622:834-841 pubmed publisher
Wu Y, Li P, Liu L, Goodwin A, Halushka P, Hirose T, et al. lncRNA Neat1 regulates neuronal dysfunction post-sepsis via stabilization of hemoglobin subunit beta. Mol Ther. 2022;30:2618-2632 pubmed publisher
product information
Product Type :
Antibody
Product Name :
HBB Polyclonal Antibody
Catalog # :
PA5-60287
Quantity :
100 uL
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:200-1:500, Western Blot: 1:500
Species :
Human
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon-gamma-G-gamma-A-delta-beta-3'.
Immunogen :
Recombinant protein corresponding to Human HBB. Recombinant protein control fragment (Product # RP-100088 ).
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:200-1:500, Western Blot: 1:500
Aliases :
beta globin chain; beta-1-globin; Beta-globin; CD113t-C; Hbb; hemoglobin beta; Hemoglobin beta chain; hemoglobin beta chain complex; hemoglobin beta chain, major-form; Hemoglobin beta-1 chain; hemoglobin subunit beta; Hemoglobin subunit beta-1; hemoglobin, beta; III beta-1 globin; III beta-2 globin; LVV-hemorphin-7; Spinorphin
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA