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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
C1orf86 Polyclonal Antibody
catalog :
PA5-58555
quantity :
100 uL
price :
US 474.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2a
Liu W, Wang G, Palovcak A, Li Y, Hao S, Liu Z, et al. Impeding the single-strand annealing pathway of DNA double-strand break repair by withaferin A-mediated FANCA degradation. DNA Repair (Amst). 2019;77:10-17 pubmed publisher
product information
Product Type :
Antibody
Product Name :
C1orf86 Polyclonal Antibody
Catalog # :
PA5-58555
Quantity :
100 uL
Price :
US 474.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 0.04-0.4 ug/mL
Species :
Human
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
Immunogen :
Recombinant protein corresponding to Human C1orf86. Recombinant protein control fragment (Product # RP-94374 ).
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 0.04-0.4 ug/mL
Aliases :
2610002J02Rik; C1orf86; Faap20; FANCA-associated protein of 20 kDa; Fanconi anemia core complex associated protein 20; Fanconi anemia core complex-associated protein 20; Fanconi anemia-associated protein of 20 kDa; FP7162; likely orthologue of H. sapiens chromosome 1 open reading frame 86 (C1orf86); LOC362678; RGD1308923; RIKEN cDNA 2610002J02 gene
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA