This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PYROXD1 Polyclonal Antibody
catalog :
PA5-58341
quantity :
100 uL
price :
US 474.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
PYROXD1 Polyclonal Antibody
Catalog # :
PA5-58341
Quantity :
100 uL
Price :
US 474.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 0.04-0.4 ug/mL
Species :
Human
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
The PYROXD1 gene encodes the protein pyridine nucleotide-disulphide oxidoreductase domain 1, which has a significant role in mitochondrial function and cellular redox homeostasis. This gene is involved in maintaining the balance of oxidative stress within cells and is crucial for the redox regulation of cellular components, impacting processes like energy metabolism and apoptosis. Mutations in PYROXD1 have been associated with early-onset myopathy, indicating its importance in muscle development and maintenance. The protein encoded by PYROXD1 is part of the oxidoreductase enzyme family that facilitates electron transfer, contributing to cellular defense against oxidative damage. Recent studies have linked PYROXD1 to various neuromuscular disorders, where disruptions in its function affect muscle fiber alignment and force production. Understanding its role in redox biology is crucial for developing therapeutic strategies to combat muscle pathologies and redox-related diseases.
Immunogen :
Recombinant protein corresponding to Human PYROXD1. Recombinant protein control fragment (Product # RP-102824 ).
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 0.04-0.4 ug/mL
Aliases :
FLJ22028; pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; pyridine nucleotide-disulphide oxidoreductase domain 1; PYROXD1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA