Cathepsin A Polyclonal Antibody | Invitrogen PA5-56629 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cathepsin A Polyclonal Antibody

catalog :

PA5-56629

quantity :

100 uL

price :

US 522.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 3g	Li X, Yu W, Qian X, Xia Y, Zheng Y, Lee J, et al. Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. Mol Cell. 2017;66:684-697.e9 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cathepsin A Polyclonal Antibody

Catalog # :

PA5-56629

Quantity :

100 uL

Price :

US 522.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 0.04-0.4 ug/mL

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The cathepsin family of proteolytic enzymes include several diverse classes of proteases. Cathepsins B, L, H, K, S and O comprise the cysteine protease class. Cathepsins D and E comprise the aspartyle protease class. The serine protease class includes cathepsin G. Cathepsins function in cellular metabolism and participate in peptide biosynthesis and protein degradation. Cathepsin A, a serine carboxypeptidase, exists in a high molecular weight lysosomal complex with b-galactosidase (b-gal) and a-neuraminidase (Neu1). Cathepsin A functions to protect b-gal and Neu1 from intralysosomal proteolysis. Deficiencies in cathepsin A lead to deficiencies in b-gal and Neu1. The gene encoding human cathepsin A maps to chromosome 20q13.12. Mutations in this gene cause glactosialidosis, a lysosomal storage disorder resulting from the b-gal and Neu1 deficiencies.

Immunogen :

Recombinant protein corresponding to Human Cathepsin A. Recombinant protein control fragment (Product # RP-102373 ).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 0.04-0.4 ug/mL

Aliases :

AU019505; beta-galactosidase 2; beta-galactosidase protective protein; carboxypeptidase C; Carboxypeptidase L; carboxypeptidase Y-like kininase; carboxypeptidase-L; cathepsin A; CTSA; deamidase; GLB2; GSL; lysosomal carboxypeptidase A; lysosomal protective protein; Lysosomal protective protein 20 kDa chain; Lysosomal protective protein 32 kDa chain; NGBE; PPCA; PPGB; protective protein cathepsin A; Protective protein for beta-galactosidase; urinary kininase

more info or order :

Invitrogen product webpage