C1orf51 Polyclonal Antibody | Invitrogen PA5-55643 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

C1orf51 Polyclonal Antibody

catalog :

PA5-55643

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Tang X, Xue D, Zhang T, Nilsson Payant B, Carrau L, Duan X, et al. A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection. Nat Cell Biol. 2023;25:381-389 pubmed publisher

product information

Product Type :

Antibody

Product Name :

C1orf51 Polyclonal Antibody

Catalog # :

PA5-55643

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:20-1:50, Western Blot: 0.04-0.4 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Transcriptional repressor which forms a negative regulatory component of the circadian clock and acts independently of the circadian transcriptional repressors: CRY1, CRY2 and BHLHE41. In a histone deacetylase-dependent manner represses the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Abrogates the interaction of ARNTL/BMAL1 with the transcriptional coactivator CREBBP and can repress the histone acetyl-transferase activity of the CLOCK-ARNTL/BMAL1 heterodimer, reducing histone acetylation of its target genes. Rhythmically binds the E-box elements (5'-CACGTG-3') on circadian gene promoters and its occupancy shows circadian oscillation antiphasic to ARNTL/BMAL1. Interacts with the glucocorticoid receptor (NR3C1) and contributes to the repressive function in the glucocorticoid response. [UniProt]

Immunogen :

Recombinant protein corresponding to Human C1orf51. Recombinant protein control fragment (Product # RP-94333 ).

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:20-1:50, Western Blot: 0.04-0.4 ug/mL

Aliases :

C1orf51; C5H1orf51; ChIP-derived repressor of network oscillator; CHRONO; Ciart; circadian associated repressor of transcription; circadian-associated transcriptional repressor; Computationally highlighted repressor of the network oscillator; GM129; hypothetical gene supported by NM_017187; RGD1566380