This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
GRPEL2 Polyclonal Antibody
catalog :
PA5-54723
quantity :
100 uL
price :
US 474.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 1
Reference
Yang R, Zhang X, Zhang Y, Wang Y, Li M, Meng Y, et al. Grpel2 maintains cardiomyocyte survival in diabetic cardiomyopathy through DLST-mediated mitochondrial dysfunction: a proof-of-concept study. J Transl Med. 2023;21:200 pubmed publisher
product information
Product Type :
Antibody
Product Name :
GRPEL2 Polyclonal Antibody
Catalog # :
PA5-54723
Quantity :
100 uL
Price :
US 474.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:20-1:50, Western Blot: 0.04-0.4 ug/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
GRPEL2 (GrpE Like 2, Mitochondrial) is a Protein Coding gene. Among its related pathways are Mitochondrial protein import and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chaperone binding. An important paralog of this gene is GRPEL1. Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
Immunogen :
Recombinant protein corresponding to Human GRPEL2. Recombinant protein control fragment (Product # RP-91013 ).
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:20-1:50, Western Blot: 0.04-0.4 ug/mL
Aliases :
actin filament-associated protein 1-like 1; Afap1l1; AFAP1-like protein 1; GrpE like 2, mitochondrial; grpE protein homolog 2, mitochondrial; Grpel2; GrpE-like 2, mitochondrial; Mt-GrpE#2; Mt-grpel2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA