SP100 Polyclonal Antibody | Invitrogen PA5-53476 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SP100 Polyclonal Antibody

catalog :

PA5-53476

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Gu X, Zhuang A, Yu J, Yang L, Ge S, Ruan J, et al. Histone lactylation-boosted ALKBH3 potentiates tumor progression and diminished promyelocytic leukemia protein nuclear condensates by m1A demethylation of SP100A. Nucleic Acids Res. 2024;52:2273-2289 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SP100 Polyclonal Antibody

Catalog # :

PA5-53476

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:200-1:500, Western Blot: 0.04-0.4 ug/mL

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.

Immunogen :

Recombinant protein corresponding to Human SP100. Recombinant protein control fragment (Product # RP-91589 ).

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:200-1:500, Western Blot: 0.04-0.4 ug/mL

Aliases :

A430075G10Rik; DKFZp686E07254; FLJ00340; FLJ34579; lysp100b; nuclear antigen Sp100; nuclear autoantigen Sp-100; Nuclear dot-associated Sp100 protein; SP 100; SP100; SP100 nuclear antigen; SP100-HMG nuclear autoantigen; speckled 100 kDa