TOMM20 Polyclonal Antibody | Invitrogen PA5-52843 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TOMM20 Polyclonal Antibody

catalog :

PA5-52843

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4a	Poon A, Saini H, Sethi S, O Sullivan G, Plun Favreau H, Wray S, et al. The role of SQSTM1 (p62) in mitochondrial function and clearance in human cortical neurons. Stem Cell Reports. 2021;16:1276-1289 pubmed publisher
	Berardini M, Gesualdi L, Morabito C, Ferranti F, Reale A, Zampieri M, et al. Simulated Microgravity Exposure Induces Antioxidant Barrier Deregulation and Mitochondria Enlargement in TCam-2 Cell Spheroids. Cells. 2023;12: pubmed publisher
	Sheng H, Lu D, Qi X, Ling Y, Li J, Zhang X, et al. A neuron-specific Isca1 knockout rat developments multiple mitochondrial dysfunction syndromes. Animal Model Exp Med. 2023;6:155-167 pubmed publisher
	Lu Q, Sun X, Yegambaram M, Ornatowski W, Wu X, Wang H, et al. Nitration-mediated activation of the small GTPase RhoA stimulates cellular glycolysis through enhanced mitochondrial fission. J Biol Chem. 2023;299:103067 pubmed publisher
	Madhu V, Hernandez Meadows M, Boneski P, Qiu Y, Guntur A, Kurland I, et al. The mitophagy receptor BNIP3 is critical for the regulation of metabolic homeostasis and mitochondrial function in the nucleus pulposus cells of the intervertebral disc. Autophagy. 2023;19:1821-1843 pubmed publisher
	H xf6 glund N, Koho N, Rossi H, Karttunen J, Mustonen A, Nieminen P, et al. Isolation of Extracellular Vesicles From the Bronchoalveolar Lavage Fluid of Healthy and Asthmatic Horses. Front Vet Sci. 2022;9:894189 pubmed publisher
	Ling Y, Ma J, Qi X, Zhang X, Kong Q, Guan F, et al. Novel rat model of multiple mitochondrial dysfunction syndromes (MMDS) complicated with cardiomyopathy. Animal Model Exp Med. 2021;4:381-390 pubmed publisher
	Madhu V, Boneski P, Silagi E, Qiu Y, Kurland I, Guntur A, et al. Hypoxic Regulation of Mitochondrial Metabolism and Mitophagy in Nucleus Pulposus Cells Is Dependent on HIF-1α-BNIP3 Axis. J Bone Miner Res. 2020;: pubmed publisher
	Grasso D, Medeiros H, Zampieri L, Bol V, Danhier P, van Gisbergen M, et al. Fitter Mitochondria Are Associated With Radioresistance in Human Head and Neck SQD9 Cancer Cells. Front Pharmacol. 2020;11:263 pubmed publisher
	Vincent G, Novak E, Siow V, Cunningham K, Griffith B, Comerford T, et al. Nix-Mediated Mitophagy Modulates Mitochondrial Damage During Intestinal Inflammation. Antioxid Redox Signal. 2020;33:1-19 pubmed publisher
	André E, De Pauw A, Verdoy R, Brusa D, Bouzin C, Timmermans A, et al. Changes of Metabolic Phenotype of Cardiac Progenitor Cells During Differentiation: Neutral Effect of Stimulation of AMP-Activated Protein Kinase. Stem Cells Dev. 2019;28:1498-1513 pubmed publisher
	Pan J, Tang F, Xiong F, Xiong L, Zeng P, Wang B, et al. APP promotes osteoblast survival and bone formation by regulating mitochondrial function and preventing oxidative stress. Cell Death Dis. 2018;9:1077 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TOMM20 Polyclonal Antibody

Catalog # :

PA5-52843

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:500-1:1,000, Western Blot: 0.04-0.4 ug/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The mitochondrial preprotein translocases of the outer membrane (Tom) is a multisubunit protein complex that facilitates the import of nucleus-encoded precursor proteins across the mitochondrial outer membrane. The Tom machinery consists of import receptors for the initial binding of cytosolically synthesized preproteins and a general import pore (GIP) for the membrane translocation of various preproteins into the mitochondria. The import receptors include Tom20 and Tom22, which form a heteromeric receptor complex that initiates the insertion of newly synthesized proteins into the outer membrane and then directs the precursor protein into the GIP. In yeast, Tom22 is the essential component of the import receptor complex as it functions as both a receptor for the preproteins and serves as a docking point for both Tom20 and the GIP.

Immunogen :

Recombinant protein corresponding to Human TOMM20. Recombinant protein control fragment (Product # RP-90451 ).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:500-1:1,000, Western Blot: 0.04-0.4 ug/mL

Aliases :

1810060K07Rik; BB284719; Gm19268; KIAA0016; MAS20; mitochondrial 20 kDa outer membrane protein; Mitochondrial import receptor subunit TOM20 homolog; mKIAA0016; MOM19; outer mitochondrial membrane receptor rTOM20; outer mitochondrial membrane receptor Tom20; TOM20; TOMM20; translocase of outer mitochondrial membrane 20; translocase of outer mitochondrial membrane 20 homolog (yeast); translocase of outer mitochondrial membrane 20 homolog type II

more info or order :

Invitrogen product webpage