CASC3 Polyclonal Antibody | Invitrogen PA5-50371 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CASC3 Polyclonal Antibody

catalog :

PA5-50371

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

CASC3 Polyclonal Antibody

Catalog # :

PA5-50371

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:25-1:100, Western Blot: 1:200-1:1,000

Species :

Human

Isotype :

IgG

Storage :

-20 C

Description :

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.

Immunogen :

Fusion protein corresponding to residues near the C terminal of human ancer susceptibility candidate 3

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:25-1:100, Western Blot: 1:200-1:1,000

Aliases :

Barentsz; barentsz protein; BTZ; cancer susceptibility candidate 3; cancer susceptibility candidate gene 3 protein; Cancer susceptibility candidate gene 3 protein homolog; Casc3; mBtz; metastatic lymph node 51; metastatic lymph node gene 51 protein; Metastatic lymph node gene 51 protein homolog; MLN 51; MLN 51 homolog; Mln51; Protein barentsz; protein CASC3