This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ARHGEF3 Polyclonal Antibody
catalog :
PA5-50116
quantity :
100 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
product information
Product Type :
Antibody
Product Name :
ARHGEF3 Polyclonal Antibody
Catalog # :
PA5-50116
Quantity :
100 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Western Blot: 1:500-1:3,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C
Description :
Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen :
Synthesized peptide derived from internal of human ARHGEF3.
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:500-1:3,000
Aliases :
1200004I24Rik; 59.8 kDA protein; 9830169H03Rik; ARHG3; ARHGEF3; C76747; DKFZP434F2429; Exchange factor found in platelets and leukemic and neuronal tissues; exchange factor found in platelets and leukemic and neuronal tissues, XPLN; GEF3; MGC118905; Rho guanine nucleotide exchange factor (GEF) 3; Rho guanine nucleotide exchange factor 3; RhoGEF protein; STA3; Xpln
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA