HnRNP Q Polyclonal Antibody | Invitrogen PA5-49767 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HnRNP Q Polyclonal Antibody

catalog :

PA5-49767

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

HnRNP Q Polyclonal Antibody

Catalog # :

PA5-49767

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:500-1:3,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation; seems not to be essential for GAIT complex function.

Immunogen :

Synthesized peptide derived from Internal of human hnRNP Q.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:500-1:3,000

Aliases :

2610109K23Rik; 4632417O19Rik; Ab2-339; Glycine- and tyrosine-rich RNA-binding protein; GRYRBP; GRY-RBP; heterogeneous nuclear ribonucleoprotein Q; hnRNP; hnRNP Q; HNRNPQ; hnRNP-Q; HNRPQ; HNRPQ1; liver regeneration-related protein LRRG077; NS1-associated protein 1; NSAP1; Nsap1l; PP68; RRM RNA binding protein GRY-RBP; synaptotagmin binding cytoplasmic RNA interacting protein; synaptotagmin binding, cytoplasmic RNA interacting protein; synaptotagmin-binding, cytoplasmic RNA-interacting protein; Syncrip