Nkx2.5 Polyclonal Antibody | Invitrogen PA5-49431 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nkx2.5 Polyclonal Antibody

catalog :

PA5-49431

quantity :

200 uL

price :

US 460.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, zebrafish

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; zebrafish ; 1:100; loading ...; fig 6g western blot; zebrafish ; 1:1000; loading ...; fig 7p	Meng Z, Liu W, Xia Y, Yin H, Zhang C, Su D, et al. The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors. Nat Commun. 2017;8:14640 pubmed publisher
	Rovina D, Castiglioni E, Mallia S, Rabino M, Farini A, Belicchi M, et al. Reprogramming of dermal fibroblasts from a Duchenne muscular dystrophy patient carrying a deletion of exons 45-50 into an induced pluripotent stem cell line (CCMi005-A). Stem Cell Res. 2022;64:102889 pubmed publisher
	Sridharan D, Palaniappan A, Blackstone B, Dougherty J, Kumar N, Seshagiri P, et al. In situ differentiation of human-induced pluripotent stem cells into functional cardiomyocytes on a coaxial PCL-gelatin nanofibrous scaffold. Mater Sci Eng C Mater Biol Appl. 2021;118:111354 pubmed publisher
	Yin H, Yan L, Liu Q, Peng Z, Zhang C, Xia Y, et al. Activating transcription factor 3 coordinates differentiation of cardiac and hematopoietic progenitors by regulating glucose metabolism. Sci Adv. 2020;6:eaay9466 pubmed publisher
	Meng X, Zhang P, Zhang L. Fetal Hypoxia Impacts on Proliferation and Differentiation of Sca-1+ Cardiac Progenitor Cells and Maturation of Cardiomyocytes: A Role of MicroRNA-210. Genes (Basel). 2020;11: pubmed publisher
	Dougherty J, Patel N, Kumar N, Rao S, Angelos M, Singh H, et al. Human Cardiac Progenitor Cells Enhance Exosome Release and Promote Angiogenesis Under Physoxia. Front Cell Dev Biol. 2020;8:130 pubmed publisher
	Jia G, Preussner J, Chen X, Guenther S, Yuan X, Yekelchyk M, et al. Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement. Nat Commun. 2018;9:4877 pubmed publisher
	Mifflin J, Dupuis L, Alcala N, Russell L, Kern C. Intercalated cushion cells within the cardiac outflow tract are derived from the myocardial troponin T type 2 (Tnnt2) Cre lineage. Dev Dyn. 2018;247:1005-1017 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Nkx2.5 Polyclonal Antibody

Catalog # :

PA5-49431

Quantity :

200 uL

Price :

US 460.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography, Protein A

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1:25, Immunocytochemistry: 1:25, Immunohistochemistry (Paraffin): 1:500, Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Immunogen :

KLH conjugated synthetic peptide between 98-133 amino acids from the Central region of mouse Nkx2-5.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:25, Immunocytochemistry: 1:25, Immunohistochemistry (Paraffin): 1:500, Western Blot: 1:1,000

Aliases :

Cardiac-specific homeobox; cardiac-specific homeobox 1; CHNG5; CSX; CSX1; Drosophila NK2 transcription factor related, locus 5; FLJ52202; FLJ97166; FLJ97195; FLJ97197; FLJ99536; HLHS2; Homeobox protein CSX; homeobox protein NK-2 homolog E; homeobox protein NKX 2-5; homeobox protein Nkx-2.5; NK2 homeobox 5; NK2 transcription factor related locus 5; NK2 transcription factor related, locus 5; NKX 2-5; NKX2.5; Nkx-2.5; Nkx-25; NKX2-5; NKX2E; NKX4-1; rNKx-2.5; tinman; tinman paralog; VSD3

more info or order :

Invitrogen product webpage