Cathepsin F Polyclonal Antibody | Invitrogen PA5-48002 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cathepsin F Polyclonal Antibody

catalog :

PA5-48002

quantity :

100 µg

price :

US 446

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

Cathepsin F Polyclonal Antibody

Catalog # :

PA5-48002

Quantity :

100 µg

Price :

US 446

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Goat

Reactivity :

Human

Applications :

Immunohistochemistry: 5-15 µg/mL, Immunoprecipitation: 25 µg/mL, Western Blot: 0.1 µg/mL

Species :

Human

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.

Immunogen :

Mouse myeloma cell line NS0-derived recombinant human Cathepsin F Ala20-Asp484

Format :

Lyophilized

Applications w/Dilutions :

Immunohistochemistry: 5-15 µg/mL, Immunoprecipitation: 25 µg/mL, Western Blot: 0.1 µg/mL

Aliases :

AI481912; Cathepsin F; CATSF; CLN13; CTSF; HGNC:2531