This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD357 (AITR/GITR) Polyclonal Antibody
catalog :
PA5-47883
quantity :
100 ug
price :
US 431.00
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
CD357 (AITR/GITR) Polyclonal Antibody
Catalog # :
PA5-47883
Quantity :
100 ug
Price :
US 431.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Goat
Reactivity :
Human
Applications :
Flow Cytometry: 2.5 ug per million cells, Immunohistochemistry (Paraffin): 5-15 ug/mL, Neutralization: Assay-Dependent, Western Blot: 0.1 ug/mL
Species :
Human
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Immunogen :
Mouse myeloma cell line NS0-derived recombinant human GITR/TNFRSF18 Gln26-Glu161 (Thr45Ala)
Format :
Lyophilized
Applications w/Dilutions :
Flow Cytometry: 2.5 ug per million cells, Immunohistochemistry (Paraffin): 5-15 ug/mL, Neutralization: Assay-Dependent, Western Blot: 0.1 ug/mL
Aliases :
Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA