PTPRS Polyclonal Antibody | Invitrogen PA5-47487 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PTPRS Polyclonal Antibody

catalog :

PA5-47487

quantity :

100 ug

price :

US 470.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

PTPRS Polyclonal Antibody

Catalog # :

PA5-47487

Quantity :

100 ug

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Goat

Reactivity :

Human

Applications :

Immunocytochemistry: 5-15 ug/mL, Western Blot: 1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

PTPRS cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycan. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for normal brain development, especially for normal development of the pituitary gland and the olfactory bulb. Functions as tyrosine phosphatase. Mediates dephosphorylation of NTRK1, NTRK2 and NTRK3. Plays a role in down-regulation of signaling cascades that lead to the activation of Akt and MAP kinases. Down-regulates TLR9-mediated activation of NF-kappa-B, as well as production of TNF, interferon alpha and interferon beta.

Immunogen :

Mouse myeloma cell line NS0-derived recombinant human PTP sigma/PTPRS Glu30-Gly1260

Format :

Lyophilized

Applications w/Dilutions :

Immunocytochemistry: 5-15 ug/mL, Western Blot: 1 ug/mL

Aliases :

AL022616; Larptp2; LAR-PTP2; Leukocyte common antigen-related protein-tyrosine phosphatase 2; leukocyte common antigen-related proten-tyrosine phosphatase 2; protein tyrosine phosphatase PTPsigma; protein tyrosine phosphatase, receptor type S; protein tyrosine phosphatase, receptor type, D; protein tyrosine phosphatase, receptor type, S; PTP; PTP-NU3; PTPNU-3; Ptprd; Ptprs; PTPsigma; Ptpsigma.; Ptpt9; Receptor-type tyrosine-protein phosphatase S; Receptor-type tyrosine-protein phosphatase sigma; Rptpd; R-PTP-S; RPTPsigma; R-PTP-sigma; tissue-specific protein tyrosine phosphatase