Neuritin Polyclonal Antibody | Invitrogen PA5-47406 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Neuritin Polyclonal Antibody

catalog :

PA5-47406

quantity :

100 µg

price :

US 418

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunocytochemistry

citations: 1

Reference
Gonzalez Figueroa P, Roco J, Papa I, Núñez Villacís L, Stanley M, Linterman M, et al. Follicular regulatory T cells produce neuritin to regulate B cells. Cell. 2021;184:1775-1789.e19 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Neuritin Polyclonal Antibody

Catalog # :

PA5-47406

Quantity :

100 µg

Pricing :

US 418

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Goat

Reactivity :

Human, Rat

Applications :

Immunocytochemistry: 5-15 µg/mL, Western Blot: 1 µg/mL

Species :

Human, Rat

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

As the nervous system of a complex organism develops, it establishes functional networks through the growth and retraction of synaptic connections from growing axons and dendrites. This synaptic remodeling involves neuro-transmitter signaling, activation of neurotrophin receptors and alterations in gene expression. One such gene whose expression is increased by neural activity is neuritin, a GPI-anchored protein that is expressed in postmitotic differentiating neurons of the developing nervous system. Its expression is also induced by the neurotrophins BDNF and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic neuronal cultures, suggesting that neuritin may play a role as a downstream effector of activity-induced neurite outgrowth. More recent experiments have shown that neuritin is required for the androgen-induced axonal elongation in motor neurons and is upregulated following spinal cord injury, suggesting that neuritin may also play a role in survival and axonal regeneration.

Immunogen :

Sf 21-derived recombinant human Neuritin Ala28-Gly114

Format :

Lyophilized

Applications w/Dilutions :

Immunocytochemistry: 5-15 µg/mL, Western Blot: 1 µg/mL

Aliases :

0710008J23Rik; Candidate plasticity gene 15 protein; candidate plasticity-related gene 15; Cpg15; dJ380B8.2; Neuritin; neuritin 1; NRN; NRN1