Nestin Polyclonal Antibody | Invitrogen PA5-47378 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nestin Polyclonal Antibody

catalog :

PA5-47378

quantity :

100 ug

price :

US 474.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

rat

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 2

Reference
Kim H, Lee Y, Kwon Y, Kim J. Efficient generation of brain organoids using magnetized gold nanoparticles. Sci Rep. 2023;13:21240 pubmed publisher
Li Y, Fan C, Wang L, Lan T, Gao R, Wang W, et al. MicroRNA-26a-3p rescues depression-like behaviors in male rats via preventing hippocampal neuronal anomalies. J Clin Invest. 2021;131: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Nestin Polyclonal Antibody

Catalog # :

PA5-47378

Quantity :

100 ug

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Goat

Reactivity :

Rat

Applications :

Immunocytochemistry: 5-15 ug/mL, Immunohistochemistry: 5-15 ug/mL, Western Blot: 0.1 ug/mL

Species :

Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.

Immunogen :

E. coli-derived recombinant rat Nestin Met544-Glu820 (Gly756Asp, Ile758Met, Arg572Lys, Ala574Pro, Ile802Met, Arg816Lys)

Format :

Lyophilized

Applications w/Dilutions :

Immunocytochemistry: 5-15 ug/mL, Immunohistochemistry: 5-15 ug/mL, Western Blot: 0.1 ug/mL

Aliases :

AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin