HBEGF Polyclonal Antibody | Invitrogen PA5-47352 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HBEGF Polyclonal Antibody

catalog :

PA5-47352

quantity :

250 µg

price :

US 436

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, neutralization, immunohistochemistry - paraffin section

citations: 1

Reference
Yang K, Yang T, Yu J, Li F, Zhao X. Integrated transcriptional analysis reveals macrophage heterogeneity and macrophage-tumor cell interactions in the progression of pancreatic ductal adenocarcinoma. BMC Cancer. 2023;23:199 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HBEGF Polyclonal Antibody

Catalog # :

PA5-47352

Quantity :

250 µg

Price :

US 436

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Goat

Reactivity :

Human

Applications :

ELISA: 0.1-0.4 µg/mL (Detection), 0.2-0.8 µg/mL (Capture), Immunohistochemistry (Paraffin): 5-15 µg/mL, Neutralization: 0.1-0.6 µg/mL, Western Blot: 0.1 µg/mL

Species :

Human

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.

Immunogen :

Sf 21-derived recombinant human HB-EGF Asp63-Leu148

Format :

Lyophilized

Applications w/Dilutions :

ELISA: 0.1-0.4 µg/mL (Detection), 0.2-0.8 µg/mL (Capture), Immunohistochemistry (Paraffin): 5-15 µg/mL, Neutralization: 0.1-0.6 µg/mL, Western Blot: 0.1 µg/mL

Aliases :

AW047313; Diphtheria toxin receptor; Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor); diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); DTR; DT-R; DTS; DTSF; GFHB; hb egf; HBEGF; Hb-egf; Hegfl; heparin binding EGF like growth factor; heparin binding epidermal growth factor-like growth factor; heparin-binding EGF-like growth factor; heparin-binding epidermal -growth - like growth factor; heparin-binding epidermal growth factor; heparin-binding epidermal -growth factor; proheparin-binding EGF-like growth factor