This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NOTCH3 Polyclonal Antibody
catalog :
PA5-47120
quantity :
100 ug
price :
US 474.00
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunohistochemistry, neutralization, flow cytometry
product information
Product Type :
Antibody
Product Name :
NOTCH3 Polyclonal Antibody
Catalog # :
PA5-47120
Quantity :
100 ug
Price :
US 474.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Goat
Reactivity :
Mouse
Applications :
Flow Cytometry: 2.5 ug per million cells, Immunohistochemistry: 5-15 ug/mL, Neutralization: Assay-Dependent, Western Blot: 0.1 ug/mL
Species :
Mouse
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Immunogen :
Sf 21-derived recombinant mouse Notch-3 Ala40-Glu468
Format :
Lyophilized
Applications w/Dilutions :
Flow Cytometry: 2.5 ug per million cells, Immunohistochemistry: 5-15 ug/mL, Neutralization: Assay-Dependent, Western Blot: 0.1 ug/mL
Aliases :
AW229011; CADASIL; CADASIL1; CASIL; hpbk; IMF2; LMNS; N3; Neurogenic locus notch homolog protein 3; notch 3; Notch 3 extracellular truncation; Notch 3 intracellular domain; Notch gene homolog 3; Notch homolog 3; NOTCH3
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA