SIGLEC5 Polyclonal Antibody | Invitrogen PA5-47058 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SIGLEC5 Polyclonal Antibody

catalog :

PA5-47058

quantity :

100 ug

price :

US 455.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Aguirre L, Montalbán Hernández K, Avendaño Ortiz J, Marín E, Lozano R, Toledano V, et al. Tumor stem cells fuse with monocytes to form highly invasive tumor-hybrid cells. Oncoimmunology. 2020;9:1773204 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SIGLEC5 Polyclonal Antibody

Catalog # :

PA5-47058

Quantity :

100 ug

Price :

US 455.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Goat

Reactivity :

Human

Applications :

Flow Cytometry: 2.5 ug per million cells, Immunohistochemistry (Paraffin): 5-15 ug/mL, Neutralization: 0.5-2.0 ug/mL, Western Blot: 0.1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.

Immunogen :

Mouse myeloma cell line NS0-derived recombinant human Siglec-5 Glu17-Thr434

Format :

Lyophilized

Applications w/Dilutions :

Flow Cytometry: 2.5 ug per million cells, Immunohistochemistry (Paraffin): 5-15 ug/mL, Neutralization: 0.5-2.0 ug/mL, Western Blot: 0.1 ug/mL

Aliases :

CD170; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OBBP2; OB-BP2; Obesity-binding protein 2; sialic acid binding Ig like lectin 5; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin F; sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; sialic acid-binding immunoglobulin-like lectin 5; sialic acid-binding lectin Siglec-F; Siglec; SIGLEC5; siglec-5; Siglecf; Siglec-F