Neuropilin 1 Polyclonal Antibody | Invitrogen PA5-47027 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Neuropilin 1 Polyclonal Antibody

catalog :

PA5-47027

quantity :

100 ug

price :

US 490.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 1

Reference
McQuaid C, Solorzano A, Dickerson I, Deane R. Uptake of severe acute respiratory syndrome coronavirus 2 spike protein mediated by angiotensin converting enzyme 2 and ganglioside in human cerebrovascular cells. Front Neurosci. 2023;17:1117845 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Neuropilin 1 Polyclonal Antibody

Catalog # :

PA5-47027

Quantity :

100 ug

Price :

US 490.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Goat

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 2.5 ug per million cells, Immunohistochemistry (Frozen): 3-15 ug/mL, Immunohistochemistry (Paraffin): 3-25 ug/mL, Neutralization: Assay-Dependent, Western Blot: 0.1 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Neuropilin 1 is a 923 amino acid containing membrane bound coreceptor to a tyrosine kinase receptor belonging to the neuropilin family with two CUB domains, two F5/8 type C domains and a MAM domain. Neuropilin 1 forms a heterodimer with NRP2 (Neuropilin 2) and is known to bind to plexin (PLXNB1) to form semaphorin receptors. Expressed mostly in the nervous system this receptor is implicated in a wide range of functions including in the development of the cardiovascular system, angiogenesis, repulsive axon guidance, formation of certain neuronal circuits, cell survival, control of neuronal migration and organogenesis outside the nervous system. This semaphorin receptor functions as receptors for both the semaphorins and vascular endothelial growth factor and is also a regulator of VEGF-induced angiogenesis. Neuropilin 1 may be involved in aggressive advanced prostate carcinoma and in the progression of breast cancer.

Immunogen :

Mouse myeloma cell line NS0-derived recombinant rat Neuropilin-1 Phe22-Ala810 (Lys811Arg), Ser829-Asp854

Format :

Lyophilized

Applications w/Dilutions :

Flow Cytometry: 2.5 ug per million cells, Immunohistochemistry (Frozen): 3-15 ug/mL, Immunohistochemistry (Paraffin): 3-25 ug/mL, Neutralization: Assay-Dependent, Western Blot: 0.1 ug/mL

Aliases :

A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R