LILRB2 Polyclonal Antibody | Invitrogen PA5-46983 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LILRB2 Polyclonal Antibody

catalog :

PA5-46983

quantity :

100 ug

price :

US 514.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig s4e	Zhao P, Xu Y, Jiang L, Fan X, Ku Z, Li L, et al. LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions. Mol Neurodegener. 2022;17:44 pubmed publisher

product information

Product Type :

Antibody

Product Name :

LILRB2 Polyclonal Antibody

Catalog # :

PA5-46983

Quantity :

100 ug

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Goat

Reactivity :

Human

Applications :

Flow Cytometry: 2.5 ug per million cells, Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 3-25 ug/mL, Neutralization: 0.3-1.0 ug/mL, Western Blot: 0.1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

LILRB2 (ILT4) gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Mouse myeloma cell line NS0-derived recombinant human LILRB2/CD85d/ILT4 Gly24-His458

Format :

Lyophilized

Applications w/Dilutions :

Flow Cytometry: 2.5 ug per million cells, Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 3-25 ug/mL, Neutralization: 0.3-1.0 ug/mL, Western Blot: 0.1 ug/mL

Aliases :

CD85 antigen-like family member D; CD85D; CD85d antigen; Ig-like transcript 4; ILT4; ILT-4; leucocyte Ig-like receptor B2; leukocyte immunoglobulin like receptor B2; leukocyte immunoglobulin-like receptor subfamily B member 2; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3; LILRB2; Lilrb3; LIR2; LIR-2; LIR2CD85D; MIR10; MIR-10; MIR10LILRA6; monocyte/macrophage immunoglobulin-like receptor 10; myeloid inhibitory receptor 10; Neutrophil immunoglobulin-like receptor 1; Nilr1; NILR-1; paired-Ig-like receptor B; Pirb; type 1 one-pass transmembrane Ig-like receptor

more info or order :

Invitrogen product webpage