Epiregulin Polyclonal Antibody | Invitrogen PA5-46969 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Epiregulin Polyclonal Antibody

catalog :

PA5-46969

quantity :

100 ug

price :

US 514.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, neutralization

citations: 1

Reference
Yang S, Zhang Y, Guo C, Liu R, Elkharti M, Ge Z, et al. The homeostatic malfunction of a novel feedback pathway formed by lncRNA021545, miR-330-3p and epiregulin contributes in hepatocarcinoma progression via mediating epithelial-mesenchymal transition. Am J Cancer Res. 2022;12:2492-2525 pubmed

product information

Product Type :

Antibody

Product Name :

Epiregulin Polyclonal Antibody

Catalog # :

PA5-46969

Quantity :

100 ug

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Goat

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Neutralization: 0.3-1.5 ug/mL, Western Blot: 0.1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.

Immunogen :

E. coli-derived recombinant human Epiregulin Val63-Leu108

Format :

Lyophilized

Applications w/Dilutions :

ELISA: Assay-Dependent, Neutralization: 0.3-1.5 ug/mL, Western Blot: 0.1 ug/mL

Aliases :

Ep; Epiregulin; EPR; ER; EREG; Proepiregulin