FOLR2 Polyclonal Antibody | Invitrogen PA5-45768 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FOLR2 Polyclonal Antibody

catalog :

PA5-45768

quantity :

100 uL

price :

US 460.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry

citations: 2

Reference
Liu J, Chen H, Liu Y, Shen Y, Meng F, Kaniskan H, et al. Cancer Selective Target Degradation by Folate-Caged PROTACs. J Am Chem Soc. 2021;143:7380-7387 pubmed publisher
Nigro A, Frattaruolo L, Fava M, De Napoli I, Greco M, Comandè A, et al. Bortezomib-Loaded Mesoporous Silica Nanoparticles Selectively Alter Metabolism and Induce Death in Multiple Myeloma Cells. Cancers (Basel). 2020;12: pubmed publisher

product information

Product Type :

Antibody

Product Name :

FOLR2 Polyclonal Antibody

Catalog # :

PA5-45768

Quantity :

100 uL

Price :

US 460.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 5 ug/mL, Surface plasmon resonance: Assay-dependent, Western Blot: 1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.

Immunogen :

Synthetic peptide directed towards the C-terminal of human FOLR2 (aa 182-231).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 ug/mL, Surface plasmon resonance: Assay-dependent, Western Blot: 1 ug/mL

Aliases :

BETA-HFR; FBP; FBP/PL-1; Fbp2; folate binding protein; folate binding protein 2; folate receptor 2; folate receptor 2 (fetal); folate receptor beta; folate receptor, beta; folate receptor, fetal/placental; Folate-binding protein 2; folate-binding protein, fetal/placental; Folbp2; Folbp-2; FOLR2; FR-beta; FR-P3; placental folate-binding protein