CYP11B1 Polyclonal Antibody | Invitrogen PA5-45063 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CYP11B1 Polyclonal Antibody

catalog :

PA5-45063

quantity :

100 uL

price :

US 481.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

product information

Product Type :

Antibody

Product Name :

CYP11B1 Polyclonal Antibody

Catalog # :

PA5-45063

Quantity :

100 uL

Price :

US 481.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Non-human primate

Applications :

Immunohistochemistry: 1:1,000, Western Blot: 1:100

Species :

Human, Non-human primate

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The steroid 11beta-hydroxylase gene, also designated Cyp11b-1, is a marker for the functional differentiation of cells in the zonae fasciculata reticularis. The deduced protein CYP11B1 consists of 466 amino acids containing a secretory signal, epidermal growth factor-like repeats, and a proteolytically inactive cathepsin B-related sequence. A related protein, human aldosterone synthase (CYP11B2), is involved in substrate recognition and conversion, with a functionally significant residue 112 in the N-terminal region of human CYP11B2. The inherited disorder glucocorticoid-remediable aldosteronism is caused by a chimeric gene duplication between the CYP11B1 and CYP11B2 genes. This disorder is characterized by hyperaldosteronism and high levels of 18-hydroxycortisol and 18-oxocortisol, which are under ACTH control.

Immunogen :

Synthetic peptide directed towards the C-terminal of human CYP11B1 (aa 331-380).

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 1:1,000, Western Blot: 1:100

Aliases :

11-beta-hydroxylase; AA389061; aldosterone synthase; Cp11ba; CPN1; CYP11B; CYP11B1; Cyp11b-1; CYPXIB1; Cytochrome P450 11B1, mitochondrial; cytochrome P450 family 11 subfamily B member 1; cytochrome p450 XIB1; cytochrome P450(11 beta)-DS; cytochrome P450, family 11, subfamily b, polypeptide 1; cytochrome P450, subfamily 11B, polypeptide 1; cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1; Cytochrome P450, subfamily XIB, polypeptide 1 (steroid 11-beta-hydroxylase); cytochrome P450C11; cytochrome P-450c11; DKFZp686B05283; FHI; FLJ36771; P450(11 beta)-DS; P450C 11; P450C11; RATCP11BA; S11BH; steroid 11-beta-hydroxylase; steroid 11-beta-hydroxylase, CYP11B1; steroid 11-beta-monooxygenase; steroid-11-beta-hydroxylase