SLC6A11 Polyclonal Antibody | Invitrogen PA5-45004 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SLC6A11 Polyclonal Antibody

catalog :

PA5-45004

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 1

Reference
Nayak D, Weadick B, Persaud A, Raj R, Shakya R, Li J, et al. EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer. iScience. 2022;25:104193 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SLC6A11 Polyclonal Antibody

Catalog # :

PA5-45004

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Slc6a11 encode GABA transporters that are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) and mediate the rapid removal of GABA and maintain low extracellular levels. Four 12-TM domain transporters have been identified and localized to neurons and glia. The protein encoded by the Slc6a11 gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in the Slc6a11 gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for the Slc6a11 gene. Diseases associated with SLC6A11 include Tricuspid Valve Stenosis and Pulmonary Valve Insufficiency.

Immunogen :

Synthetic peptide directed towards the C-terminal of human SLC6A11 (aa 577-626).

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1 ug/mL

Aliases :

D930045G19Rik; E130202I16Rik; GABA transporter 3; GABA transporter GAT-3; GABT3; Gabt4; gamma-aminobutyric acid (GABA-A) transporter 4; Gat3; GAT-3; Gat4; GAT-4; Gat-b; SLC6A11; Sodium- and chloride-dependent GABA transporter 3; sodium- and chloride-dependent GABA transporter 4; solute carrier family 6 (neurotransmitter transporter), member 11; solute carrier family 6 (neurotransmitter transporter, GABA), member 11; solute carrier family 6 member 11