K-Ras Polyclonal Antibody | Invitrogen PA5-44339 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

K-Ras Polyclonal Antibody

catalog :

PA5-44339

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

citations: 6

Reference
Booth L, West C, Hoff D, Dent P. GZ17-6.02 and Doxorubicin Interact to Kill Sarcoma Cells via Autophagy and Death Receptor Signaling. Front Oncol. 2020;10:1331 pubmed publisher
Dent P, Booth L, Roberts J, Poklepovic A, Hancock J. (Curcumin+sildenafil) enhances the efficacy of 5FU and anti-PD1 therapies in vivo. J Cell Physiol. 2020;: pubmed publisher
Booth L, Roberts J, West C, Von Hoff D, Dent P. GZ17-6.02 initiates DNA damage causing autophagosome-dependent HDAC degradation resulting in enhanced anti-PD1 checkpoint inhibitory antibody efficacy. J Cell Physiol. 2020;: pubmed publisher
Booth L, Roberts J, Poklepovic A, Dent P. The Lethality of [Pazopanib + HDAC Inhibitors] Is Enhanced by Neratinib. Front Oncol. 2019;9:650 pubmed publisher
Dent P, Booth L, Roberts J, Liu J, Poklepovic A, Lalani A, et al. Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells. Oncogene. 2019;38:5890-5904 pubmed publisher
Moll H, Pranz K, Musteanu M, Grabner B, Hruschka N, Mohrherr J, et al. Afatinib restrains K-RAS-driven lung tumorigenesis. Sci Transl Med. 2018;10: pubmed publisher

product information

Product Type :

Antibody

Product Name :

K-Ras Polyclonal Antibody

Catalog # :

PA5-44339

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Western Blot: 0.2-1 ug/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

K-RAS (GTPase KRas) belongs to the Ras oncogene family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. It plays an important role in the regulation of cell proliferation and has a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes in colorectal cancer cells in a ZNF304-dependent manner. Mutations in the gene can result in leukemia acute myelogenous, leukemia juvenile myelomonocytic, Noonan Syndrome, gastric cancer, and cardiofaciocutaneous syndrome 2.

Immunogen :

Synthetic peptide directed towards the N-terminal of human KRAS (aa 2-51).

Format :

Liquid

Applications w/Dilutions :

Western Blot: 0.2-1 ug/mL

Aliases :

AI929937; cellular c-Ki-ras2; cellular c-Ki-ras2 proto-oncogene; CFC2; c-Ki-ras; c-Kirsten-ras protein; c-Kirsten-ras proto-oncogene; c-K-ras; c-K-ras2 protein; fa04e08; fc14b12; fc23g10; fj89d12; GTPase KRas; GTPase KRas, N-terminally processed; hypothetical protein LOC445289; K RAS; ki-Ras; Kirsten rat sarcoma oncogene 2, expressed; Kirsten rat sarcoma viral (Kras-2) oncogene homolog; Kirsten rat sarcoma viral oncogene; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma viral oncogene homologue 2 (active); KRAS; K-ras; K-Ras 2; K-ras p21 protein; KRAS proto-oncogene, GTPase; KRAS1; Kras2; Kras-2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; NS; NS3; oncogene KRAS2; p21; p21 protein; p21B; p21ras; PR310 c-K-ras oncogene; RALD; ras; ras p21; RASK; RASK2; ras-like protein; transforming protein p21; Unknown; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; wu:fa04e08; wu:fc14b12; wu:fc23g10; wu:fj89d12; xRAS2; zgc:85725